Drug Standards

Medchemexpress LLC Flavopiridol hydrochloride (alvocidib hydrochloride) | 131740-09-5 | MFCD26792554 | 438.30 g/mol | C21H21Cl2NO5 | 10 MG

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Flavopiridol hydrochloride (alvocidib) is an ATP-competitive, broad-spectrum cyclin-dependent kinase (CDK) inhibitor used in research to probe cell-cycle control, autophagy, and viral pathways. The hydrochloride salt enhances solubility for in vitro and in vivo applications; manufacturer datasheet provides IC50s, solubility, storage, and formulation guidance for stock and dosing preparation.

• ATP-competitive cyclin-dependent kinase inhibitor.
• Reported IC50s: CDK1 30 nM, CDK2 170 nM, CDK4 100 nM.
• High solubility in DMSO and water (≥20 mg/mL) for stock solutions.
• Includes in vivo formulation guidance for dosing preparations.
• Stability in solvent: -80°C (1 year) and -20°C (6 months) when sealed.
• Molecular weight 438.30 g/mol and formula C21H21Cl2NO5 for accurate calculations.

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Apexbio Technology LLC Fluconazole hydrate 155347-36-7 5g

Fluconazole hydrate (CAS 155347-36-7) is a small-molecule inhibitor targeting the fungal enzyme lanosterol 14 -demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane integrity and arresting fungal growth Fluconazole hydrate exerts its biological activity primarily through inhibition of lanosterol 14 -demethylase In in vitro studies fluconazole hydrate demonstrates inhibitory activity with documented IC50 values typically ranging from 0 1 to 10 g/mL depending on fungal strain and experimental conditions Based on these pharmacological properties fluconazole hydrate holds research potential in antifungal pharmacology assays fungal infection model studies and evaluation of combinational antifungal therapies

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Medchemexpress LLC Stearyl gallate | 10361-12-3 | 10 G

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Stearyl gallate is an alkyl gallate characterized by a long alkyl chain (18 carbons). It demonstrates both antioxidant activity and weak antiviral properties, specifically against HSV-1.

• Exhibits antioxidant activity
• Shows weak antiviral activity against HSV-1
• Has a purity of 99.50%
• Appears as a white to off-white solid
• Stable under recommended storage conditions
• Melting point of 95°C
• Soluble in DMSO

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Sigma Aldrich Fine Chemicals Biosciences Duloxetine Related Compound F United States Pharmacopeia (USP) Reference Standard | 1104890-90-5 | 10MG

Duloxetine Related Compound F United States Pharmacopeia (USP) Reference Standard | Mol Wt: 333.88 | 1104890-90-5 | 10MG

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Medchemexpress LLC (Rac)-Moxifloxacin ((Rac)-BAY 12-8039 free base) | 354812-41-2 | 99.5% | C21H24FN3O4 | 5 MG

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Rac-Moxifloxacin is an isoform of Moxifloxacin Hydrochloride, an oral 8-methoxyquinolone antimicrobial. It is used for treating acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.

• Is an oral 8-methoxyquinolone antimicrobial.
• Used in the treatment of acute bacterial sinusitis.
• Used in the treatment of acute bacterial exacerbations of chronic bronchitis.
• Used in the treatment of community-acquired pneumonia.
• Acts rapidly in vitro, with effects observed within the first 3 hours and complete broth sterilization within 24 hours.
• Appears to offer a protective effect against macrophage lysis in vitro.
• Demonstrates efficacy in vivo, leading to longer survival in treated subjects and reduced bacterial overgrowth in spleens and lungs without toxicity.

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Selleck Chemical LLC Niraparib (MK-4827) S2741-50mg

Niraparib (MK-4827) is a selective inhibitor of PARP1/2 with IC50 of 3 8 nM/2 1 nM with great activity in cancer cells with mutant BRCA-1 and BRCA-2 It is 330-fold selective against PARP3 V-PARP and Tank1 Niraparib can form PARP DNA complexes resulting in DNA damage apoptosis and cell death Phase 3

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Selleck Chemical LLC Istradefylline 5mg 155270-99-8 KW-6002

Istradefylline (KW-6002) is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

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Apexbio Technology LLC Orally active inhibitor of ALK kinase. Entrectinib 5mg. 223387-75-5. MFCD23136998

Orally active inhibitor of ALK kinase. Entrectinib 5mg. 223387-75-5. MFCD23136998

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Sigma Aldrich Fine Chemicals Biosciences 5-Aza-2′-deoxycytidine | 2353-33-5 | MFCD00043011 | 50 mg

5-Aza-2′-deoxycytidine | Purity: ≥97% | Mol Wt: 228.21 | 2353-33-5 | MFCD00043011 | 50 mg

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Medchemexpress LLC Ticagrelor impurity 11 | 220352-36-3 | ≥95.0% | C10H8F2O2 | 5 G

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Ticagrelor impurity 11 is an impurity of Ticagrelor. It appears as a solid with a molecular weight of 198.17. This product is for research use only.

• Purity: ≥95.0%
• Storage as powder: -20 °C for 3 years, 4 °C for 2 years
• Storage in solvent: -80 °C for 6 months, -20 °C for 1 month

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Selleck Chemical LLC Tofacitinib (CP-690550) 10mg 477600-75-2 Tasocitinib

Tofacitinib (CP-690550,Tasocitinib) is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis. *For Research & Development use only.  Product is not intended for drug, household, or human consumption.

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Medchemexpress LLC Methyl 2-oxo-1,3-dihydroindole-4-carboxylate | 90924-46-2 | MFCD08277245 | 100mg

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Nintedanib impurity 10 is an impurity of Nintedanib (HY-50904)

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Sigma Aldrich Fine Chemicals Biosciences Risperidone British Pharmacopoeia (BP) Reference Standard | 106266-06-2 | MFCD00274576 |

Risperidone British Pharmacopoeia (BP) Reference Standard | Mol Wt: 410.48 | 106266-06-2 | MFCD00274576 |

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